Primal Calm 60 Capsules

Primal Calm 60 Capsules is a scientifically formulated dietary supplement designed to support healthy stress response and promote a sense of calm and relaxation. Each bottle contains a 30-day supply of 60 vegetarian capsules.

Active Ingredients:
The key active ingredients in Primal Calm include:

- Phosphatidylserine (100 mg): A phospholipid that plays a crucial role in cellular function, particularly in the brain. Research suggests it may help modulate cortisol levels and support cognitive function under stress.

- L-Theanine (100 mg): An amino acid found naturally in green tea that has been shown to promote relaxation without drowsiness. Studies indicate it may help reduce stress and anxiety while improving focus.

- Magnolia Bark Extract (200 mg): Contains bioactive compounds like honokiol and magnolol that have demonstrated anxiolytic and neuroprotective properties in preclinical studies. 

- Rhodiola Rosea Extract (150 mg): An adaptogenic herb that may help the body adapt to physical, chemical, and environmental stress. Clinical trials suggest it can reduce fatigue and enhance mental performance under stressful conditions.

- Ashwagandha Root Extract (125 mg): Another adaptogen with a long history of use in Ayurvedic medicine. Modern research indicates it may help lower cortisol levels and reduce symptoms of stress and anxiety.

Mechanism of Action:
Primal Calm works through multiple pathways to support the body's stress response:

1. Cortisol Modulation: Phosphatidylserine and ashwagandha have been shown to help regulate cortisol, the primary stress hormone.

2. GABA Enhancement: L-theanine and magnolia bark may increase levels of gamma-aminobutyric acid (GABA), a neurotransmitter that promotes relaxation.

3. Adaptogenic Support: Rhodiola and ashwagandha help the body adapt to stressors, potentially improving resilience over time.

4. Antioxidant Effects: Several ingredients provide antioxidant protection, which may help mitigate oxidative stress associated with chronic stress.

Clinical Evidence:
Multiple ingredients in Primal Calm have been subject to clinical trials:

- A double-blind, placebo-controlled study found that phosphatidylserine supplementation (300 mg/day) blunted cortisol response to acute stress in healthy men.

- In a randomized controlled trial, L-theanine (200 mg/day) reduced stress-related symptoms and improved cognitive function in healthy adults under stress.

- A systematic review of 11 randomized controlled trials concluded that Rhodiola rosea supplementation can significantly reduce symptoms of fatigue and enhance cognitive function under stress.

Dosage and Administration:
The recommended dosage is 2 capsules daily, preferably with meals or as directed by a healthcare professional. For optimal results, consistent daily use for at least 4-6 weeks is advised.

Safety and Contraindications:
Primal Calm is generally well-tolerated. However, as with any dietary supplement, individuals with pre-existing medical conditions, pregnant or nursing women, and those taking medications should consult their healthcare provider before use. Mild side effects such as gastrointestinal discomfort or headache have been reported in rare cases.

Quality Assurance:
Primal Calm is manufactured in a GMP-certified facility and undergoes rigorous third-party testing for purity and potency. It is free from common allergens, artificial colors, and preservatives.

Primal Calm 60 Capsules offers a comprehensive, evidence-based approach to stress management. By combining adaptogenic herbs with neuroactive compounds, it aims to support the body's natural stress response mechanisms and promote overall well-being. While individual results may vary, the ingredients in Primal Calm have demonstrated potential benefits for stress reduction, cognitive function, and resilience in clinical studies.